Clinical Epidemiology#
25 papers
Global dynamics of a compartmental model to assess the effect of transmission from deceased#
2023 · Mathematical Biosciences
This paper presents a compartmental model for the spread of a disease with an imperfect vaccine, considering transmission from deceased infected. The global dynamics are analyzed through Lyapunov func…
Projecting vaccine demand and impact for emerging zoonotic pathogens#
2024 · BMC Medicine
The paper develops a modeling framework to assess sustainable vaccine manufacturing needs and potential impact of outbreak response for four priority pathogens: Lassa virus, Nipah virus, MERS coronavi…
Optimal control analysis for the Nipah infection with constant and time-varying vaccination and treatment under real data application#
2024 · Scientific Reports
This paper formulates a mathematical model to analyze the dynamics and optimal control of Nipah virus (NiV). The model considers human-to-human and food-borne transmission, as well as contact with an …
Global and regional mortality statistics of nipah virus from 1994 to 2023: a comprehensive systematic review and meta-analysis#
2024 · Pathogens and Global Health
This paper reports a significant increase in the global mortality rate of Nipah virus from 54.1% (2004–2013) to 80.1% (2014–2023). India has the highest mortality rate at 82.7% (1994–2023), and enceph…
Observational study on the clinical epidemiology of infectious acute encephalitis syndrome including Nipah virus disease, Bangladesh: BASE cohort study protocol#
2025 · BMJ Open
This paper describes a prospective cohort study in Bangladesh aimed at characterizing the patient population, clinical features, treatment practices, common aetiologies and outcomes in patients presen…
A Comparative Analysis of Statistical Methods to Estimate the Reproduction Number in Emerging Epidemics, With Implications for the Current Coronavirus Disease 2019 (COVID-19) Pandemic#
2024 · Clinical Infectious Diseases
This paper compares seven statistical methods to estimate the reproduction number (R0) in emerging epidemics, focusing on the COVID-19 pandemic, and finds that most methods overestimate R0 in the earl…
Predictors of mortality among critically ill SARS-CoV-2 infected patients—a retrospective cohort study, Kerala, India#
2025 · Front. Public Health
This paper is a retrospective cohort study identifying predictors of mortality among critically ill SARS-CoV-2 infected patients in Kerala, India.
Mapping the distribution of Nipah virus infections: a geospatial modelling analysis#
2024 · Lancet Planet Health
This study maps the distribution of Nipah virus infections using geospatial modeling analysis.
Exact calculation of end-of-outbreak probabilities using contact tracing data#
2023 · Journal of the Royal Society Interface
This paper presents a method for calculating the exact end-of-outbreak probability using contact tracing data, which can inform public health policymakers about when an infectious disease outbreak has…
Exact calculation of end-of-outbreak probabilities using contact tracing data#
2023 · Journal of the Royal Society Interface
This paper presents a new method for calculating the probability that an infectious disease outbreak has ended using contact tracing data.
A systematic review on Nipah virus: global molecular epidemiology and medical countermeasures development#
2024 · Virus Evolution
This paper conducts a systematic review on the global epidemiology and research advancements of Nipah virus, aiming to identify key knowledge gaps in the literature.
Nipah Virus Encephalitis Reemergence, Bangladesh#
2001 · Not specified in the text
Two outbreaks of encephalitis in Meherpur and Naogaon, Bangladesh, occurred in 2001 and 2003. The paper investigates these outbreaks, identifies cases through serum sampling, and suggests that transmi…
Ribavirin Therapy for Nipah Virus Infection#
2004 · Journal of Virology
This paper presents a study on the effectiveness of ribavirin therapy in treating Nipah virus infection in mice and humans, contradicting a previous statement that ribavirin was ineffective based on l…
Infectious Causes of Acute Encephalitis Syndrome in India – Decadal Change and the Way Forward#
2023 · Not specified from text
This paper discusses changes in the causes of Acute Encephalitis Syndrome (AES) in India over the past decade, with a focus on the rise of Nipah virus and other infections like Chandipura, chikungunya…
Henipavirus Encephalitis: Recent Developments and Advances#
2015 · Brain Pathology
This paper discusses the clinical manifestations and pathological features of Hendra virus (HeV) and Nipah virus (NiV), which cause severe and often fatal outbreaks in humans and animals.
Antibody response in symptomatic & asymptomatic Nipah virus cases from Kerala, India#
2021 · Indian J Med Res
The study evaluates antibody response among symptomatic survivors of NiV infection and their asymptomatic contacts identified during 2018 and 2019 NiV outbreaks from Kerala, India.
Advancements in Nipah virus treatment: Analysis of current progress in vaccines, antivirals, and therapeutics#
2024 · Immunology
This paper discusses the current progress in NiV-vaccine research and therapeutic options, including mAbs and antiviral medications.
‘The Bug Stops Here!’ Nipah Encephalitis; Kerala#
2019
A case study of a man with Nipah encephalitis presenting with high fever, neurological symptoms, and MRI findings of multiple tiny hyperintensities throughout the brain (Starry sky appearance). The pa…
Neurologic Manifestations of the World Health Organization’s List of Pandemic and Epidemic Diseases#
2021 · Frontiers in Neurology
This paper reviews the neurological manifestations of diseases with epidemic or pandemic potential as viewed through a neurologist’s lens.
Improving clinical care of patients in Nipah outbreaks: moving beyond ‘compassionate use’#
2024 · The Lancet Regional Health - Southeast Asia
This paper discusses strategies to improve the clinical care for patients in Nipah outbreaks, focusing on enhancing early case detection, optimizing supportive care, adopting a syndromic approach, and…
Beyond neurology: unravelling Nipah virus’s cardiovascular conundrum—an editorial#
Not specified in the text
This editorial discusses the cardiovascular implications of Nipah virus infection beyond its neurological manifestations.
MR Imaging Features of Nipah Encephalitis#
2000 · AJR
This paper describes MRI findings of Nipah encephalitis in 31 patients, revealing discrete high-signal-intensity lesions disseminated throughout the brain, mainly in the subcortical and deep white mat…
Stakeholder Perspective of Handling the Deceased during the Nipah Virus Outbreak in Kerala, South India, 2018#
2020 · American Journal of Tropical Medicine and Hygiene
This paper analyzes the stakeholder response during the handling of deceased individuals during the Nipah virus outbreak in Kerala, South India, 2018 using a qualitative study and grounded theory appr…
Lessons from the Nipah virus outbreak in Malaysia#
2007 · Malaysian J Pathol
The Nipah virus outbreak in Malaysia (1998/1999) resulted in 265 cases of acute encephalitis with 105 deaths and caused near total collapse of the billion-dollar pig-farming industry. The paper discus…
Nipah Virus-associated Encephalitis Outbreak, Siliguri, India#
2001 · Not specified in the text
An outbreak of febrile illness associated with altered sensorium was observed in Siliguri, India. Laboratory investigations initially failed to identify an infectious agent, but retrospective analysis…