Advancements in Nipah virus treatment: Analysis of current progress in vaccines, antivirals, and therapeutics • Nipah Virus Research Library

Authors: Gayatree Mishra, Vishal Prajapat, Debasis Nayak

Year: 2024

Journal: Immunology

DOI: 10.1111/imm.13695

Summary#

This paper discusses the current progress in NiV-vaccine research and therapeutic options, including mAbs and antiviral medications.

Key Findings#

Several potential vaccine candidates have been developed and tested in animal models
Some of these candidate vaccines have entered further clinical trials
Research has identified a handful of therapeutic monoclonal antibodies (mAbs) capable of neutralizing the virion
Progress in discovering potential antiviral drugs has been limited

Methodology#

Study Type: Review
Geographic Focus: South-Asian and South-East Asian countries, Africa, and Australia

Topics#

Vaccines, Antivirals, Therapeutics, Nipah virus

Relevance#

The paper is crucial for fast-tracking ongoing projects related to vaccine clinical trials, anti-NiV therapeutics due to NiV’s pandemic potential.

Source#

[Download PDF](/pdfs/clinical-manifestations/Immunology - 2023 - Mishra - Advancements in Nipah virus treatment Analysis of current progress in vaccines antivirals .pdf)