Authors: Mandeep S. Chadha, James A. Comer, Luis Lowe, Paul A. Rota, Pierre E. Rollin, William J. Bellini, Thomas G. Ksiazek, Akhilesh C. Mishra
Year: 2001
Journal: Not specified in the text
DOI: Not specified in the text
PMID: Not specified in the text
Summary#
An outbreak of febrile illness associated with altered sensorium was observed in Siliguri, India. Laboratory investigations initially failed to identify an infectious agent, but retrospective analysis detected NiV-specific antibodies and RNA in 9 patients and 5 urine samples respectively.
Key Findings#
- NiV-specific immunoglobulin M (IgM) and IgG antibodies were detected in 9 of 18 patients.
- Reverse transcription–polymerase chain reaction (RTPCR) assays detected RNA from NiV in urine samples from 5 patients.
Methodology#
- Study Type: Retrospective analysis
- Sample Size: 18 patients
- Geographic Focus: Siliguri, India and Bangladesh
- Time Period: January - February 2001
Topics#
Epidemiology, Virology
Relevance#
This paper reports the first detection of Nipah virus in India, expanding the geographic range of this zoonotic disease.