Authors: Deekshitha Alla, Dhruv Jayeshkumar Shah, Navaneethan Adityaraj, Moparthi Vagdevi, Sai Santhosha Mrudula Alla, Krithi Sree, Praneeth Aitha, Ram Prasanjith Reddy Bollampalli, Antony Joseph Pathinangil, Krupa Patel, Yussif Issaka
Year: 2024
Journal: Medicine®
DOI: 10.xxxx/xxxxx or null
PMID: PMID or null
Summary#
This paper conducts a systematic review of case reports on Nipah virus infection to examine geographic distribution, mortality, transmission pathways, and available methods for diagnosis and treatment.
Key Findings#
- 80% frequency of fever, 47% myalgia, 47% headache, 44.1% shortness of breath/acute respiratory distress syndrome, 44.1% altered sensorium, and 42.6% vomiting.
- RT-PCR is the most commonly used diagnostic test.
- Direct human contact with infected patients is the most common route of transmission.
- Treatment modalities include interventional procedures, antiviral drugs, and symptomatic treatment.
- Seizures (39.2%) and altered sensorium (35.7%) are the most common complications.
Methodology#
- Study Type: Systematic Review
- Sample Size: N = 92 cases analyzed from 12 studies
- Geographic Focus: Asia
- Time Period: Years not specified
Topics#
Epidemiology, Virology, Clinical
Relevance#
The review emphasizes the importance of early Nipah virus infection diagnosis and treatment to prevent life-threatening consequences.