Authors: Biplab Adhikari
Year: 2025
Journal: Acta Medica (Hradec Králové)
DOI: 10.14712/18059694.2025.11
Summary#
This paper discusses the significance of henipaviruses (Hendra and Nipah viruses) as zoonotic threats with high mortality rates and limited therapeutic options. It highlights recent discoveries and the need for expanded research into effective antivirals, vaccines, and enhanced surveillance.
Key Findings#
- Henipaviruses (HeV and NiV) have high mortality rates in humans (60% and 92% respectively)
- Clinical presentation of henipaviruses can range from mild influenza-like symptoms to severe encephalitis and/or respiratory failure
- First reported case of henipavirus was in Australia in 1994, followed by an outbreak in Malaysia in 1998–1999
Methodology#
- Study Type: Review
Topics#
Henipaviruses, Zoonotic diseases, Epidemiology, Public health
Relevance#
The paper emphasizes the need for expanded research into effective antivirals, vaccines, and enhanced surveillance due to henipaviruses’ high mortality rates and limited therapeutic options.