Authors: Anna Rosa Garbuglia, Daniele Lapa, Silvia Pauciullo, Hervé Raoul, Delphine Pannetier
Year: 2023
Journal: Viruses
DOI: 10.3390/v15102062
Summary#
This paper provides an overview of the current status of diagnostics for Nipah virus (NiV), a high mortality rate zoonosis. Early diagnosis is crucial to limit outbreaks and provide appropriate care. qRT-PCR is currently considered optimal for acute NiV infection assessment, with different sensitivities depending on the platform used.
Key Findings#
- qRT-PCR is the optimum method for acute NiV infection assessment
- Nasal swabs, cerebrospinal fluid, urine, and blood are used for RT-PCR testing
- Different sensitivities have been observed depending on the platform used
- An international standard for NiV is yet to be established
- The diagnosis of NiV should be included in a more global One Health approach
Methodology#
- Study Type: Review
Topics#
Virology, Epidemiology
Relevance#
The paper highlights the importance of efficient diagnosis of Nipah virus for improved surveillance and preparedness in endemic countries.