Authors: Jagadish Joshi, Yogendra Shah, Kishor Pandey, Ram Prashad Ojha, Chet Raj Joshi, Lok Raj Bhatt, Shyam Prakash Dumre, Pushpa Raj Acharya, Hem Raj Joshi, Shikha Rimal, Ramesh Shahi, Deepak Pokharel, Kamal Singh Khadka, Bimal Dahal, Saroj Nepal, Ram Singh Dhami, Krishna Prasad Pant, Rajdip Basnet, Basu Dev Pandey
Year: 2023
Journal: Tropical Medicine and Health
DOI: 10.1186/s41182-023-00535-7
Summary#
This paper reviews the epidemiology, pathogenesis, molecular surveillance, transmission dynamics, genetic diversity, reservoir host, clinical characteristics, and phylogenetics of Nipah virus in South and South East Asia.
Key Findings#
- Nipah virus is a major public health challenge in South and South East Asia
- Phylogenetic analysis confirmed two primary clades of Nipah virus are in circulation
- In humans, Nipah virus causes severe respiratory illness and/or deadly encephalitis
- Nipah virus is mainly diagnosed by ELISA along with PCR
Methodology#
- Study Type: Review
- Geographic Focus: South and South East Asia
Topics#
Nipah virus, Epidemiology, Clinical, Virology
Relevance#
The paper highlights the importance of adopting a One Health approach to reduce the risk of zoonotic disease transmission in the region.