Authors: Arindam Ganguly, Saptarshi Mahapatra, Shibsankar Ray, Sayantan Chattopadhyay, Md. Jabiul Islam, Sathi Garai, Tapas Kumar Dutta, Manasi Chattaraj, Sourav Chattaraj
Year: 2025
Journal: Virology Journal
DOI: 10.1186/s12985-025-02728-4
Summary#
This paper reviews the epidemiology, clinical features, and modes of transmission of Nipah virus infection, its geographical distribution, and endemic regions.
Key Findings#
- NiV is a highly virulent zoonotic infectious agent that poses a significant threat to public health.
- The virus can spread via different routes, including zoonotic spillover and human-to-human transmission.
- Clinical manifestations include mild respiratory illness and severe and fatal encephalitis with a case fatality rate of 40 to 75%.
- NiV has been reported in Malaysia, Bangladesh, and India, with fruit bats serving as natural reservoirs.
Methodology#
- Study Type: Review
- Geographic Focus: Malaysia, Bangladesh, and India
Topics#
Epidemiology, Virology, Clinical
Relevance#
The review highlights the challenges in managing disease outbreaks of Nipah virus infection and emphasizes the need for immediate attention and coordinated global action.