Authors: Anita M. Shete, Rajlaxmi Jain, Sreelekshmy Mohandas, Prachi Pardeshi, Pragya D. Yadav, Nivedita Gupta, Devendra Mourya
Year: 2024
Journal: Indian J Med Res
DOI: 10.4103/ijmr.ijmr_2737_21
Summary#
The paper develops and evaluates IgM and IgG ELISAs for detecting Nipah virus antibodies in human sera, demonstrating high specificity and sensitivity.
Key Findings#
- 99.28% specificity and 100% sensitivity of the developed anti-NiV IgM ELISA compared to reference test
- 90% positive predictive value and 93.94% positive predictive value for anti-Nipah IgM ELISA and IgG ELISA respectively with test accuracy of 99.33%
Methodology#
- Study Type: Laboratory Study
- Sample Size: Not specified
- Geographic Focus: India
Topics#
Virology, Diagnostic Tests
Relevance#
The development of these ELISAs can aid in timely diagnosis and management of Nipah virus cases, particularly during outbreaks.