Authors: Thomas P. Monath, Richard Nichols, Friederike Feldmann, Amanda Griffin, Elaine Haddock, Julie Callison, Kimberly Meade-White, Atsushi Okumura, Jamie Lovaglio, Patrick W. Hanley, Chad S. Clancy, Carl Shaia, Wasima Rida, Joan Fusco
Year: 2023
Journal: Front. Immunol.
DOI: 10.3389/fimmu.2023.1216225
Summary#
This paper investigates immunological correlates of protection afforded by PHV02, a recombinant vesicular stomatitis virus vector vaccine against Nipah virus disease in the African green monkey model. Neutralizing antibody to Nipah virus is proposed as the principal mediator of protection.
Methodology#
- Study Type: Original Research
- Sample Size: Not specified in text
- Geographic Focus: Not specified in text
- Time Period: Not specified in text
Topics#
Vaccine Development, Virology
Relevance#
This paper provides insights into the immunological correlates of protection afforded by PHV02, a potential vaccine against Nipah virus disease. Further research could lead to the development of effective vaccines and interventions.