Authors: Rishav Madhukalya, Urvashi Yadav, Hilal Ahmad Parray, Nisha Raj, Santhik Subhasingh Lupitha, Vivek Kumar, Anjali Saroj, Vidushi Agarwal, Dilip Kumar, Supratik Das, Rajesh Kumar
Year: 2025
Journal: Applied Microbiology and Biotechnology
DOI: 10.1007/s00253-025-13474-6
Summary#
This paper is a detailed review on Nipah virus, covering its origin and spread, modes of transmission, risk factors, genome, key proteins, pathogenesis, clinical features, diagnostics, and ongoing research for therapies.
Key Findings#
- Nipah virus has high pandemic potential
- No clinically approved antivirals, immunotherapy, or vaccines available for NiV infection
- Discussion on different diagnostic approaches and ongoing research for NiV therapies
Methodology#
- Study Type: Review
Topics#
Epidemiology, Clinical, Virology, Policy
Relevance#
The paper is important for Nipah research due to its focus on pandemic preparedness, novel diagnostic and therapeutic approaches, global threat from biosafety level 4 pathogens, and animal models for NiV research.