Authors: Aaron J., Priyamvada Acharya
Year: 2024
Journal: Viruses
DOI: 10.3390/v16020195
Summary#
This paper reviews the available structural information on Henipavirus glycoproteins, which are important for understanding viral entry and developing vaccines and therapies.
Key Findings#
- Henipaviruses rely on two surface glycoproteins (attachment and fusion proteins) for host cell entry.
- The attachment protein is a tetrameric structure, but its biologically relevant states are unclear.
Methodology#
- Study Type: Review
Topics#
Viruses, Glycoproteins, Paramyxoviridae, Viral Entry
Relevance#
The study is significant for understanding the mechanisms that drive Henipavirus fusion and developing vaccines and therapies.