Authors: Oscar Cortes-Azuero, Noémie Lefrancq, Birgit Nikolay, Clifton McKee, Julien Cappelle, Vibol Hul, Tey Putita Ou, Thavry Hoem, Philippe Lemey, Mohammed Ziaur Rahman, Ausraful Islam, Emily S. Gurley, Veasna Duong, Henrik Salje
Year: 2024
Journal: The Journal of Infectious Diseases
DOI: 10.xxxx/xxxxx
Summary#
This paper investigates the genetic diversity of Nipah virus across spatial scales using a comprehensive collection of genomes from bats and humans over 22 years in six countries.
Key Findings#
- Average of 2.4 co-circulating genetic clusters within any bat roost, rising to 5.5 clusters at areas of 1500–2000 km²
- Each genetic cluster occupies an average area of 1.3 million km² (95% confidence interval [CI], .6–2.3 million km²)
- In concentrated genomic surveillance sites in Bangladesh and Cambodia, only approximately 15% of overall NiV diversity has been uncovered
Methodology#
- Study Type: Study Type not explicitly mentioned
- Sample Size: N = 257
- Geographic Focus: [‘6 countries’]
- Time Period: 1999–2020
Topics#
Epidemiology, Virology, Genetics
Relevance#
The findings provide valuable insights into the genetic diversity of Nipah virus, which is crucial for understanding its transmission dynamics and developing control strategies.