Authors: Bronwyn A. Clayton, Deborah Middleton, Rachel Arkinstall, Leah Frazer, LinFa Wang, Glenn A. Marsh
Year: 2016
Journal: PLoS Negl Trop Dis
DOI: 10.1371/journal.pntd.0004775
Summary#
This paper investigates the differences in transmission of Nipah viruses between Malaysia and Bangladesh in ferrets, suggesting a contributory mechanism for increased transmission of NiV-BD compared to NiV-MY due to higher levels of virus replication in respiratory tract tissues.
Key Findings#
- More rapid onset of productive infection and higher levels of virus replication in respiratory tract tissues for NiV-BD compared to NiV-MY
- Suggests a contributory mechanism for increased NiV-BD transmission between people compared to NiV-MY
Methodology#
- Study Type: Time Course Study
- Sample Size: Ferrets
Topics#
Virology
Relevance#
This paper sheds light on the differences in transmission of Nipah viruses between Malaysia and Bangladesh, which has implications for understanding and controlling outbreaks.