Authors: Hongzhao Li, Ji-Young V. Kim, Bradley S. Pickering
Year: 2023
Journal: Frontiers in Microbiology
DOI: 10.3389/fmicb.2023.1167085
Summary#
This paper reviews the outbreaks, animal hosts, and potential new emergence of Henipavirus zoonotic pathogens (Hendra virus and Nipah virus) causing severe neurological and respiratory disease.
Key Findings#
- HeV has caused sporadic infections in horses and a small number of human cases in Australia since 1994.
- NiV Malaysia genotype (NiV-M) was responsible for the 1998–1999 epizootic outbreak in pigs with spillover to humans in Malaysia and Singapore.
- Since 2001, the NiV Bangladesh genotype (NiV-B) has been the predominant strain leading to outbreaks almost every year in Bangladesh and India, with hundreds of infections in humans.
Methodology#
- Study Type: Review
- Geographic Focus: Australia, Malaysia, Singapore, Bangladesh, India
- Time Period: 1994-Present
Topics#
Epidemiology, Virology
Relevance#
This review paper provides insights into the transmission pathways of henipaviruses from bats to humans, highlighting the importance of understanding these pathways for disease control and prevention.