Authors: Shahneaz Ali Khan, Abu Zubayer Tanzin, Mohammed Ashif Imtiaz, Md Mazharul Islam, Ariful Islam, Mohammad Mahmudul Hassan
Year: 2024
Journal: Journal not specified in the text
DOI: 10.1002/vms3.835
Summary#
This paper is a systematic review and meta-analysis analyzing data on bat-originated viral zoonotic diseases in Asia and Africa, focusing on their respiratory cellular tropism, susceptibility, and overall likelihood of causing pandemics.
Key Findings#
- The pooled estimates of case fatality rates of bat-originated viral zoonotic diseases were higher in Africa (61.06%, 95%CI: 50.26 to 71.85, l2 % = 97.3, p < 0.001).
- Estimates of case fatality rates were higher in Ebola (61.06%; 95%CI: 50.26 to 71.85, l2 % = 97.3, p < 0.001) followed by Nipah (55.19%; 95%CI: 39.29 to 71.09, l2 % = 94.2, p < 0.001), MERS (18.49%; 95%CI: 8.19 to 28.76, l2 % = 95.4, p < 0.001) and SARS (10.86%; 95%CI: 6.02 to 15.71, l2 % = 85.7, p < 0.001) with the overall case fatality rates of 29.86 (95%CI: 29.97 to 48.58, l2 % = 99.0, p < 0.001).
- Bat-originated viruses have caused several outbreaks of deadly diseases, including Nipah, Ebola, SARS and MERS in Asia and Africa.
Methodology#
- Study Type: Systematic Review and Meta-Analysis
- Sample Size: Data analyzed from multiple studies
- Geographic Focus: Asia and Africa
- Time Period: Not specified in the text
Topics#
Virology, Epidemiology, Clinical
Relevance#
This paper provides insights into the potential for bat-originated viruses to cause pandemics, focusing on case fatality rates and geographical distribution of several deadly diseases.