Pathogenicity and virulence of henipaviruses

Authors: Benjamin Kaza, Hector C. Aguilar

Year: 2023

Journal: VIRULENCE

DOI: 10.1080/21505594.2023.2273684

Summary

This paper reviews the pathogenesis, replication cycle, epidemiology, genomics, and host responses of henipaviruses, including Nipah (NiV), Hendra (HeV), Langya (LayV), Gamak (GAKV), and CedV.

Key Findings

• Henipaviruses are responsible for a range of respiratory and neurological diseases in humans and animals.
• NiV and HeV are maintained in fruit bat reservoirs and can spillover into humans or animals.
• Recent advances in surveillance have revealed a high number of henipaviral genome sequences distributed across most continents.
• Emerging henipaviruses include Langya (LayV) and Mojiang (MojV), which infect shrews and rats, respectively.

Methodology

• Study Type: Review

Topics

Epidemiology, Clinical, Virology

Relevance

This review provides a comprehensive overview of the current knowledge on henipaviruses, which are important for understanding the emergence and potential threats posed by these viruses.

Source

View the entire paper: File:Pathogenicity and virulance of henipavirus.pdf