Characterization of Nipah Virus from Outbreaks in Bangladesh, 2008–2010

Authors: Michael K. Lo, Luis Lowe, Kimberly B. Hummel, Hossain M.S. Sazzad, Emily S. Gurley, M. Jahangir Hossain, Stephen P. Luby, David M. Miller, James A. Comer, Pierre E. Rollin, William J. Bellini, Paul A. Rota

Year: 2018

Journal: Emerging Infectious Diseases

DOI: 10.3201/eid1802.111492

Summary

This paper characterizes the complete genomic sequences of Nipah Virus isolates from two patients in Bangladesh in 2008 and partial sequences from three patients in 2010. The sequences were found to be distinct, indicating multiple co-circulating lineages in a localized region over a short time.

Key Findings

Identical NiV isolates found in two patients in Bangladesh in 2008
Three genetically distinct sequences found from patients in Faridpur and Gopalganj districts in January–March 2010
Proposal of a standardized protocol for genotyping Nipah Virus

Methodology

Study Type: Observational
Sample Size: 5 patients
Geographic Focus: Bangladesh
Time Period: 2008-2010

Topics

Virology, Epidemiology

Relevance

The findings provide insights into the genetic diversity and transmission patterns of Nipah Virus in Bangladesh, which is crucial for understanding and controlling outbreaks.

Source

View the entire paper: File:11-1492 finalR.pdf