View source for Nipah virus: pathogenesis, genome, diagnosis, and treatment

'''Authors:''' Rishav Madhukalya, Urvashi Yadav, Hilal Ahmad Parray, Nisha Raj, Santhik Subhasingh Lupitha, Vivek Kumar, Anjali Saroj, Vidushi Agarwal, Dilip Kumar, Supratik Das, Rajesh Kumar

'''Year:''' 2025

'''Journal:''' Applied Microbiology and Biotechnology

'''DOI:''' 10.1007/s00253-025-13474-6

=== Summary ===
This paper is a detailed review on Nipah virus, covering its origin and spread, modes of transmission, risk factors, genome, key proteins, pathogenesis, clinical features, diagnostics, and ongoing research for therapies.

=== Key Findings ===
* Nipah virus has high pandemic potential
* No clinically approved antivirals, immunotherapy, or vaccines available for NiV infection
* Discussion on different diagnostic approaches and ongoing research for NiV therapies

=== Methodology ===
* '''Study Type:''' Review

=== Topics ===
Epidemiology, Clinical, Virology, Policy

=== Relevance ===
The paper is important for Nipah research due to its focus on pandemic preparedness, novel diagnostic and therapeutic approaches, global threat from biosafety level 4 pathogens, and animal models for NiV research.

=== Source ===
View the entire paper: [[File:253_2025_Article_13474.pdf]]