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Sero-prevalence of Nipah antibodies among close contacts of the index case during 2019 Ernakulam outbreak

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Authors: Reshmi Ramachandran, Merin S. Jose, Rima R. Sahay, Anita Shete

Year: 2022

Journal: Journal of Family Medicine and Primary Care

DOI: 10.4103/jfmpc.jfmpc_1731_21

Summary

This paper investigates subclinical or asymptomatic Nipah infection amongst the close contacts of an index case in the 2019 Ernakulam outbreak by testing for NiV-specific IgM and IgG antibodies. None of the 49 contacts tested positive.

Key Findings

  • None of the 49 contacts tested positive for anti-NiV human IgM and IgG antibodies.
  • There were no subclinical cases amongst the close contacts of Nipah index case during the 2019 Kerala outbreak.

Methodology

  • Study Type: Observational
  • Sample Size: 49 close contacts
  • Geographic Focus: Ernakulam district, Kerala, India
  • Time Period: 2019

Topics

Nipah virus, Asymptomatic infection, IgM and IgG antibodies

Relevance

The study provides insights into the absence of subclinical Nipah cases among close contacts of an index case during the 2019 Kerala outbreak.

Source

View the entire paper: File:JFMPC-11-2479.pdf

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