Dissecting an Outbreak: A Clinico-epidemiological Study of Nipah Virus Infection in Kerala, India, 2018
Authors: Bhargavan Pallivalappil, Althaf Ali, NK Thulaseedharan, Ummer Karadan, Jayakrishnan Chellenton, KP Dipu, AS Anoop Kumar, KG Sajeeth Kumar, TP Rajagopal, KP Suraj, GR Santosh Kumar, RN Supreeth, Mounika Yelisetti, Prathap Reddy Muthyala, KS Aryasree, KS Apurva Rao
Year: 2018
Journal: Not specified in the text
DOI: Not specified in the text
PMID: Not specified in the text
Summary
This paper describes the clinical characteristics and epidemiology of a Nipah virus outbreak in Kerala, India in May 2018. It identifies that out of 23 patients with Nipah virus infection, 91.3% expired, with common features including fever, altered sensorium, tachycardia, hypertension, and shortness of breath.
Key Findings
- Out of 23 patients with Nipah virus infection, 21 (91.3%) expired
- Only the index case was infected in the community from fruit bats. Rest of the cases were due to transmission at three public hospitals.
- Median age was 45 years. 65% of them were males.
- Median incubation period was 9.5 days.
- The rapid spread of infection uncovered the miserable state of health care system in implementing infection control measures.
Methodology
- Study Type: Clinico-epidemiological Study
- Sample Size: 23 patients with Nipah virus infection
- Geographic Focus: Kerala, India
- Time Period: May 2018
Topics
Nipah Virus, Epidemiology, Clinical
Relevance
The paper highlights the need for appropriate treatments, vaccines, and diagnostics due to the high case fatality rate and socio-economic burden of Nipah virus infections.
Source
View the entire paper: File:JGID-12-21.pdf