Pandemic potential of the Nipah virus and public health strategies adopted during outbreaks: Lessons from Kerala, India

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Authors: Thekkumkara Surendran Anish ID1,2‡, Reghukumar Aravind ID3‡, Chandni Radhakrishnan4‡, Nivedita Gupta ID5‡, Pragya D. Yadav ID6‡, Jerin Jose Cherian ID5,7‡*, Rima Sahay ID6‡, Shubin Chenayil ID8‡, Anoop Kumar A. S. ID9‡, Anitha Puduvail Moorkoth ID10‡, Ashadevi, Velichapat Ramakrishnan Lathika, Shamsudeen Moideen ID12, Sekhar Lukose Kuriakose ID13, Kalathil Joseph Reena11‡, Thomas Mathew14‡

Year: 2024

Journal: PLOS GLOBAL PUBLIC HEALTH

Summary

This review highlights the relevance of surveillance and health system preparedness, infection control, early diagnosis and treatment with broad-spectrum antivirals, environmental conservation, and community engagement in mitigating Nipah outbreaks. It also emphasizes the importance of developing new biologicals and anti-viral drugs to combat the disease.

Key Findings

  • The review discusses the available evidence on the spillover mechanisms, genetic attributes of the circulating virus, ecological factors, risk of hospital-based superspreading, treatment outcomes
  • Successful strategies employed in Kerala in response to the recurrent Nipah outbreaks were highlighted

Methodology

  • Study Type: Review
  • Sample Size: Not applicable (literature review)
  • Geographic Focus: Kerala, India
  • Time Period: 2018 and beyond

Topics

Epidemiology, Virology, Policy

Relevance

The paper matters for Nipah research as it provides insights into strategies employed in Kerala to manage recurrent outbreaks and emphasizes the need for developing new biologicals and anti-viral drugs.

Source

View the entire paper: File:Anish et al. - 2024 - Pandemic potential of the Nipah virus and public health strategies adopted during outbreaks Lessons.pdf