Nipah Virus: An Overview of the Current Status of Diagnostics and Their Role in Preparedness in Endemic Countries

Authors: Anna Rosa Garbuglia, Daniele Lapa, Silvia Pauciullo, Hervé Raoul, Delphine Pannetier

Year: 2023

Journal: Viruses

DOI: 10.3390/v15102062

Summary

This paper provides an overview of the current status of diagnostics for Nipah virus (NiV), a high mortality rate zoonosis. Early diagnosis is crucial to limit outbreaks and provide appropriate care. qRT-PCR is currently considered optimal for acute NiV infection assessment, with different sensitivities depending on the platform used.

Key Findings

qRT-PCR is the optimum method for acute NiV infection assessment
Nasal swabs, cerebrospinal fluid, urine, and blood are used for RT-PCR testing
Different sensitivities have been observed depending on the platform used
An international standard for NiV is yet to be established
The diagnosis of NiV should be included in a more global One Health approach

Methodology

Study Type: Review

Topics

Virology, Epidemiology

Relevance

The paper highlights the importance of efficient diagnosis of Nipah virus for improved surveillance and preparedness in endemic countries.

Source

View the entire paper: File:Viruses-15-02062.pdf