Molecular Pathogenesis of Nipah Virus

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Authors: Pratik Talukdar, Debankita Dutta, Elija Ghosh, Indrani Bose, Sourish Bhattacharjee

Year: 2023

Journal: Applied Biochemistry and Biotechnology

DOI: 10.1007/s12010-022-04300-0

Summary

This paper reviews Nipah virus (NiV), a zoonotic disease causing encephalitis and severe respiratory illness in humans, primarily carried by Pteropus spp. bats. It discusses the need for clinical trials to establish potential treatment regimens.

Key Findings

  • Nipah virus is a zoonotic disease that can cause lethal encephalitis and severe respiratory illness in humans
  • The virus is primarily carried by Pteropus spp. bats
  • Human-to-human transmission can occur
  • Multiple outbreaks have been reported from South and Southeast Asia recently

Methodology

  • Study Type: Review Article
  • Geographic Focus: South and Southeast Asia
  • Time Period: From the discovery of NiV in 1998

Topics

Nipah virus, Encephalitis, Epidemiology, Pathology

Relevance

The paper highlights the urgent need for clinical trials to develop treatment regimens against NiV due to its potential threat to community health and repeated outbreaks in South and Southeast Asia.

Source

View the entire paper: File:12010 2022 Article 4300.pdf