Authors: Rishav Madhukalya, Urvashi Yadav, Hilal Ahmad Parray, Nisha Raj, Santhik Subhasingh Lupitha, Vivek Kumar, Anjali Saroj, Vidushi Agarwal, Dilip Kumar, Supratik Das, Rajesh Kumar
Year: 2025
Journal: Applied Microbiology and Biotechnology
DOI: 10.1007/s00253-025-13474-6
Summary
This paper is a detailed review on Nipah virus, covering its origin and spread, modes of transmission, risk factors, genome, key proteins, pathogenesis, clinical features, diagnostics, and ongoing research for therapies.
Key Findings
- Nipah virus has high pandemic potential
- No clinically approved antivirals, immunotherapy, or vaccines available for NiV infection
- Discussion on different diagnostic approaches and ongoing research for NiV therapies
Methodology
- Study Type: Review
Topics
Epidemiology, Clinical, Virology, Policy
Relevance
The paper is important for Nipah research due to its focus on pandemic preparedness, novel diagnostic and therapeutic approaches, global threat from biosafety level 4 pathogens, and animal models for NiV research.
Source
View the entire paper: File:253 2025 Article 13474.pdf