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Characterization of TheWe: Isolation and Phylogenetic Analysis of Nipah Virus from Pteropus vampyrus Bats

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Authors: Sohayati A. Rahman, Sharifah S. Hassan, Kevin J. Olival, Maizan Mohamed, Li-Yen Chang, Latiffah Hassan, Norsharina M. Saad, Syamsiah A. Shohaimi, Zaini C. Mamat, M.S. Naim, Jonathan H. Epstein, Arshad S. Suri, Hume E. Field, Peter Daszak

Year: 2016

Journal: Emerging Infectious Diseases

DOI: 10.3201/eid1612.091790

Summary

The paper isolates and characterizes Nipah virus (NiV) from Pteropus vampyrus bats, the suspected reservoir for a 1998 outbreak in Malaysia. The study provides evidence of viral recrudescence and shows that these bats can harbor latent infections.

Key Findings

  • NiV is isolated from Pteropus vampyrus bats, the suspected reservoir for a 1998 outbreak in Malaysia
  • The study provides evidence of viral recrudescence in these bats
  • The isolated NiV is monophyletic with previous NiVs in combined analysis

Methodology

  • Study Type: Prospective Cohort Study
  • Sample Size: 17 P. vampyrus bats
  • Geographic Focus: 2 locations in Malaysia
  • Time Period: June 2004 through June 2005

Topics

Epidemiology, Virology

Relevance

The paper contributes to understanding the mechanisms of transmission between individual bats and viral maintenance in a colony, which are poorly understood.

Source

View the entire paper: File:09-1790 finalD.pdf

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