Seroprevalence of Nipah virus and related paramyxoviruses in native frugivorous bats, Luzon, Philippines
Authors: Marana S. Rekedala, Mary-Glazel Noroñac, Jairue Azel P. Caféc, Neil Mittala, Sophie A. Borthwick, Kirk J. Taraya, Jezryl Jaeger L. Garcia, Samantha L. Magsano, Hazel R. Cruze, Dorothy Jane Manzano, Lianying Yana, Dolyce H. W. Low, David T. S. Hayman, Mary Grace Dacumae, Catalino Demetriac, Phillip A. Alviola, Fedelino F. Malbasc, Gavin J. D. Smith, Eric D. Laing
Year: 2025
Journal: Emerging Microbes & Infections
DOI: 10.1080/22221751.2025.2555720
Summary
This paper identifies wildlife bat hosts of Nipah virus by conducting monthly serological surveillance across Luzon, Philippines and finds a 13.92% NiV seroprevalence in native flying foxes.
Key Findings
- 13.92% NiV seroprevalence in native flying foxes
- NiV neutralizing activity detected in some flying fox sera
- Age and seasonality as drivers of high anti-NiV antibody levels
- Less than 10% NiV seroprevalence in R. amplexicaudatus, C. luzoniensis, and P. jagori bats
- No detectable neutralizing antibodies in the mentioned bat species
Methodology
- Study Type: Serological Surveillance
- Sample Size: Monthly serological surveillance of flying foxes and other native frugivorous bat species across Luzon
- Geographic Focus: Luzon, Philippines
- Time Period: Not specified
Topics
Nipah virus, Bats, Philippines, Biosurveillance, Spillover risk
Relevance
This study highlights a major wildlife host of Nipah virus in an understudied region, which could aid in understanding and mitigating the spillover risk.
Source
View the entire paper: File:TEMI 14 2555720.pdf