Henipavirus zoonosis: outbreaks, animal hosts and potential new emergence

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Authors: Hongzhao Li, Ji-Young V. Kim, Bradley S. Pickering

Year: 2023

Journal: Frontiers in Microbiology

DOI: 10.3389/fmicb.2023.1167085

Summary

This paper reviews the outbreaks, animal hosts, and potential new emergence of Henipavirus zoonotic pathogens (Hendra virus and Nipah virus) causing severe neurological and respiratory disease.

Key Findings

  • HeV has caused sporadic infections in horses and a small number of human cases in Australia since 1994.
  • NiV Malaysia genotype (NiV-M) was responsible for the 1998–1999 epizootic outbreak in pigs with spillover to humans in Malaysia and Singapore.
  • Since 2001, the NiV Bangladesh genotype (NiV-B) has been the predominant strain leading to outbreaks almost every year in Bangladesh and India, with hundreds of infections in humans.

Methodology

  • Study Type: Review
  • Geographic Focus: Australia, Malaysia, Singapore, Bangladesh, India
  • Time Period: 1994-Present

Topics

Epidemiology, Virology

Relevance

This review paper provides insights into the transmission pathways of henipaviruses from bats to humans, highlighting the importance of understanding these pathways for disease control and prevention.

Source

View the entire paper: File:Fmicb-14-1167085.pdf