Discovery and genetic characterization of novel paramyxoviruses from small mammals in Hubei Province, Central China
Authors: Jia-le Xu, *, Jin-tao Chen, *, Bing Hu, *, Wei-wei Guo, *, Jing-jing Guo, Chao-rui Xiong, Ling-xin Qin, Xin-nai Yu, Xiao-min Chen, Kun Cai, Yi-rong Li, *, Man-qing Liu, *, Liang-jun Chen, *, Wei Hou, *
Year: 2024
Journal: Microbial Genomics
DOI: 10.1099/mgen.0.001229
Summary
Researchers discovered and characterized novel paramyxoviruses in small mammals from Hubei Province, Central China. Most of these viruses belong to the genus Jeilongvirus.
Key Findings
- 190 paramyxovirus sequences were obtained from 969 small mammals
- Viruses were classified into four clades: genera Jeilongvirus, Morbillivirus, Henipavirus and Narmovirus
- Six near-full-length genomes with different genomic organizations were recovered
- Co-divergence analysis showed host-switching occurred frequently in the evolutionary histories of the genus Jeilongvirus
Methodology
- Study Type: Hemi-nested reverse transcription PCR study
- Sample Size: 969 small mammals
- Geographic Focus: Hubei Province, Central China
Topics
Paramyxoviruses, Wildlife, Zoonotic diseases, Genome content, Evolution
Relevance
The findings highlight the high prevalence of paramyxoviruses, particularly jeilongviruses, and underscore the diversity of these viruses and their genome content, as well as the evolutionary histories of the genus Jeilongvirus.
Source
View the entire paper: File:Mgen-10-01229.pdf