Nipah Open Library

Laboratory Diagnosis of Hendra and Nipah: Two Emerging Zoonotic Diseases with One Health Significance

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Authors: Shaun van den Hurk, Aurelle Yondo, Binu T. Velayudhan

Year: 2025

Journal: Viruses

DOI: 10.3390/v17071003

Summary

This review synthesizes current knowledge on the epidemiology, transmission dynamics, and pathogenesis of Nipah virus (NiV) and Hendra virus (HeV), discussing molecular and serological diagnostic tools for their identification.

Key Findings

  • The paper discusses RT-PCR, ELISA, and LAMP assays for diagnosing HeV and NiV.
  • Diagnostics are crucial for rapid identification of cases and disease surveillance.
  • Emphasis is placed on diagnostics suitable for low-income areas.
  • Further development of diagnostic assays, including isothermal amplification tests and other next-generation approaches, is recommended.

Methodology

  • Study Type: Review

Topics

Epidemiology, Clinical, Virology

Relevance

The paper discusses the importance of diagnostic tests for Hendra and Nipah viruses, which are highly pathogenic and have no human vaccines available.

Source

View the entire paper: File:Viruses-17-01003.pdf

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