Nipah Open Library

Advancements in Nipah virus treatment: Analysis of current progress in vaccines, antivirals, and therapeutics

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Authors: Gayatree Mishra, Vishal Prajapat, Debasis Nayak

Year: 2024

Journal: Immunology

DOI: 10.1111/imm.13695

Summary

This paper discusses the current progress in NiV-vaccine research and therapeutic options, including mAbs and antiviral medications.

Key Findings

  • Several potential vaccine candidates have been developed and tested in animal models
  • Some of these candidate vaccines have entered further clinical trials
  • Research has identified a handful of therapeutic monoclonal antibodies (mAbs) capable of neutralizing the virion
  • Progress in discovering potential antiviral drugs has been limited

Methodology

  • Study Type: Review
  • Geographic Focus: South-Asian and South-East Asian countries, Africa, and Australia

Topics

Vaccines, Antivirals, Therapeutics, Nipah virus

Relevance

The paper is crucial for fast-tracking ongoing projects related to vaccine clinical trials, anti-NiV therapeutics due to NiV’s pandemic potential.

Source

View the entire paper: File:Immunology - 2023 - Mishra - Advancements in Nipah virus treatment Analysis of current progress in vaccines antivirals .pdf

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