'The Bug Stops Here!’ Nipah Encephalitis; Kerala

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Year: 2019

Summary

A case study of a man with Nipah encephalitis presenting with high fever, neurological symptoms, and MRI findings of multiple tiny hyperintensities throughout the brain (Starry sky appearance). The patient was treated with Ribavirin, IVIG, and isolation precautions.

Key Findings

  • Nipah infection (NiV) recently claimed 17 lives in Kerala Outbreak of May 2018
  • The patient presented with high grade fever, chills, rigors, fever, conjunctival congestion, drowsiness, dysarthria, severe ataxia, myoclonus, tachycardia, and tachypnea
  • MRI showed multiple tiny hyperintensities throughout the cerebral hemispheres, cerebellum, and ponto-mesencephalic area with restricted diffusion (Starry sky appearance)
  • CSF tested positive for NiV on day 2
  • The patient was started on oral Ribavirin for 11 days

Methodology

  • Study Type: Case Study
  • Sample Size: 1
  • Geographic Focus: Kerala, India
  • Time Period: May 2018

Topics

Nipah, Encephalitis, MRI, Ribavirin, Case Study

Relevance

The case study highlights the presentation, diagnosis, and treatment of a patient with Nipah encephalitis, providing insights into the disease's neurological manifestations and potential treatment options.

Source

View the entire paper: File:The bug stops here nipah encephalitis kerala.51.pdf