Community willingness to participate in a Nipah vaccine trial in Bangladesh

Authors: Nazmun Nahar, Shahana Parveen, Emily S. Gurley, Probir Kumar Ghosh, Ishrat Jabeen, Md. Rifat Haidar, Farhat Jahan, Mohammad Saeed Munim, Kanij Fatema Chanda, Md. Wazed Ali, Zubair Akhtar, Tahmina Shirin, Sayera Banu, Atique Iqbal Chowdhury, Asraful Alam, Brian E. Dawes, Joan Fusco, Thomas P. Monath, Gray Heppner, Stephen P. Luby

Year: 2025

Journal: Vaccine

DOI: 10.xxxx/xxxxx

Summary

This paper explores people's knowledge about Nipah virus and their willingness to participate in a vaccine trial in Bangladesh.

Key Findings

Many participants were aware of NiV and expressed willingness to participate in a vaccine trial.
Concerns about vaccine safety and side effects affected participation decisions.
More respondents from Mirpur township, Dhaka, had heard about Nipah virus and were willing to participate than those from Faridpur.

Methodology

Study Type: Mixed methods (qualitative and quantitative)
Sample Size: 66 in-depth interviews and 978 survey interviews
Geographic Focus: Mirpur township, Dhaka, and Faridpur District, Bangladesh
Time Period: December 2021 to November 2022

Topics

Vaccine trial, Investigational vaccine, Nipah virus infection, Bangladesh

Relevance

The findings suggest that a Nipah vaccine trial may be feasible in Bangladesh, with clear communication on safety and side effects being important for informed participation.

Source

View the entire paper: File:1-s2.0-S0264410X25008758-main.pdf