Evidence for Nipah virus recrudescence and serological patterns of captive Pteropus vampyrus

Authors: A. R. SOHAYATI, L. HASSAN, *, S. H. SHARIFAH, K. LAZARUS, C. M. ZAINI, J. H. EPSTEIN, N. SHAMSYUL NAIM, H. E. FIELD, S. S. ARSHAD, J. ABDUL AZIZ, P. DASZAK, *

Year: 2011

Journal: Epidemiol Infect

DOI: 10.1017/S0950268811000550

Summary

This study aimed to describe the transmission dynamics and serological patterns of Nipah virus in Pteropus vampyrus bats over a 1-year period. The findings suggest that NiV circulates in wild bat populations, antibody could be maintained for long periods, maternal antibodies against NiV are transmitted passively, and NiV was isolated from the urine of one bat.

Key Findings

Five NiV serological patterns were found
NiV circulates in wild bat populations
Antibody can be maintained for long periods
Maternal antibodies against NiV are transmitted passively and last up to 14 months
NiV was isolated from the urine of one bat, leading to seroconversion in two other bats

Methodology

Study Type: Observational
Sample Size: Number of Pteropus vampyrus bats sampled over a 1-year period
Geographic Focus: Ipoh, Peninsular Malaysia
Time Period: 2009 to 2010

Topics

Nipah virus, Pteropus vampyrus, serological patterns, transmission dynamics

Relevance

The study provides evidence for the circulation of Nipah virus in wild bat populations, the maintenance of antibodies for long periods, and the transmission of maternal antibodies. This information is crucial for understanding and preventing future outbreaks of Nipah virus.

Source

View the entire paper: File:Nihms394492.pdf