Henipavirus Encephalitis: Recent Developments and Advances

Authors: Kien Chai Ong, Kum Thong Wong

Year: 2015

Journal: Brain Pathology

DOI: 10.1111/bpa.12278

Summary

This paper discusses the clinical manifestations and pathological features of Hendra virus (HeV) and Nipah virus (NiV), which cause severe and often fatal outbreaks in humans and animals.

Key Findings

Both HeV and NiV cause an acute encephalitic syndrome
Pathological features include disseminated, multi-organ vasculopathy and parenchymal cell infection
Both viruses can cause relapsing encephalitis

Methodology

Study Type: Review
Geographic Focus: Australia, Malaysia, Bangladesh, India, Philippines
Time Period: 1990s to present

Topics

Epidemiology, Clinical, Virology

Relevance

The paper provides insights into the pathogenesis of henipaviruses and their potential for future spillover events into human populations.

Source

View the entire paper: File:BPA-25-605.pdf