Molecular characterization of Nipah virus from Pteropus hypomelanus in Southern Thailand

Authors: Supaporn Wacharapluesadee, Panumas Samseeneam, Mana Phermpool, Thongchai Kaewpom, Apaporn Rodpan, Pattarapol Maneeorn, Phimchanok Srongmongkol, Budsabong Kanchanasaka, Thiravat Hemachudha

Year: 2016

Journal: Virology Journal

DOI: 10.1186/s12985-016-0510-x

Summary

This study identified Nipah virus strain using molecular characterizations from Pteropus hypomelanus in southern Thailand.

Key Findings

  • Five out of 184 bat urine specimens were positive for Nipah virus using nested RT-PCR assay on partial nucleocapsid fragment
  • All 5 partial fragments and 4 whole nucleocapsid genes formed a monophyletic with NiV-MY

Methodology

  • Study Type: Short Report
  • Sample Size: 184 bat urine specimens
  • Geographic Focus: Southern Thailand

Topics

Virology, Epidemiology

Relevance

The study shows that P. hypomelanus in southern Thailand harbored similar Nipah virus to Malaysia, indicating a higher potential for a widespread NiV outbreak in Thailand.

Source

View the entire paper: File:12985 2016 Article 510.pdf