Structural Studies of Henipavirus Glycoproteins

Authors: Aaron J., Priyamvada Acharya

Year: 2024

Journal: Viruses

DOI: 10.3390/v16020195

Summary

This paper reviews the available structural information on Henipavirus glycoproteins, which are important for understanding viral entry and developing vaccines and therapies.

Key Findings

• Henipaviruses rely on two surface glycoproteins (attachment and fusion proteins) for host cell entry.
• The attachment protein is a tetrameric structure, but its biologically relevant states are unclear.

Methodology

• Study Type: Review

Topics

Viruses, Glycoproteins, Paramyxoviridae, Viral Entry

Relevance

The study is significant for understanding the mechanisms that drive Henipavirus fusion and developing vaccines and therapies.

Source

View the entire paper: File:Viruses-16-00195.pdf