View source for Hendra and Nipah Infection: Pathology, Models and Potential Therapies

'''Authors:''' Frederic Vigant, Benhur Lee

'''Year:''' 2011

'''Journal:''' Infect Disord Drug Targets

'''DOI:''' 10.xxxx/xxxxx (not provided in text)

'''PMID:''' PMID not provided in text

=== Summary ===
This paper reviews the unique features of henipavirus infections, and discusses different strategies and animal models that have been developed to identify and test potential drugs for preventing or treating henipavirus infections.

=== Key Findings ===
* Henipaviruses are zoonotic paramyxoviruses with a broader tropism than most other paramyxoviruses, and can cause severe acute encephalitis
* Ribavirin was empirically used during the Nipah virus outbreak but its efficacy is disputed
* There are currently no approved effective prophylactic or therapeutic treatments for henipavirus infections

=== Methodology ===
* '''Study Type:''' Review
* '''Sample Size:''' Not applicable (literature review)
* '''Geographic Focus:''' Australia, Malaysia
* '''Time Period:''' 1994-1998

=== Topics ===
Henipavirus, Nipah, Hendra, Inhibitors, Antivirals, Pathology, Animal Models

=== Relevance ===
This paper is important for understanding the current state of research on Henipaviruses, which have a high public health and economic threat potential.

=== Source ===
View the entire paper: [[File:nihms343752.pdf]]