View source for Henipavirus Receptor Usage and Tropism

'''Authors:''' Manuscript Author: Olivier Pernet, Manuscript Author: Benhur Lee

'''Year:''' 2012

'''Journal:''' Curr Top Microbiol Immunol.

'''DOI:''' 10.1007/82_2012_222

=== Summary ===
This paper reviews the biology of the henipavirus receptors, ephrin-B2 and ephrin-B3, and how their usage relates to henipavirus cell tropism in vitro and in vivo.

=== Key Findings ===
* Henipaviruses use ephrin-B2 and ephrin-B3 as viral entry receptors
* These receptors account for the unusual species tropism of henipaviruses

=== Methodology ===
* '''Study Type:''' Review

=== Topics ===
Virology

=== Relevance ===
This paper provides insights into the receptor usage and tropism of henipaviruses, which are biosafety level 4 (BSL4) pathogens with high mortality rates in humans. Understanding these aspects can help develop vaccines and therapeutics for these deadly viruses.

=== Source ===
View the entire paper: [[File:nihms444714.pdf]]